Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 3/20 | 0.48 |
| ▸ | FAP | Q12884 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145153 | 0.85 | HDAC8 (0.69) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL7771334 | 0.84 | HDAC8 (0.59) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL2230132 | 0.82 | HDAC8 (0.61) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL7771330 | 0.81 | HDAC8 (0.59) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL18457431 | 0.81 | HDAC8 (0.59) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL18457265 | 0.81 | PLK1 (0.62) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL15906173 | 0.81 | HDAC8 (0.51) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL15741895 | 0.80 | KMT2A (0.51) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL29370451 | 0.80 | KMT2A (0.51) | HDAC8MMP3PLK1HPGDHDAC2 | |
| SCHEMBL9830463 | 0.80 | PPARG (0.58) | HDAC8MMP3PLK1HPGDHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | disclosed |
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | disclosed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | disclosed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | disclosed |
| WO-2010132992-A1 | COMPOUNDS FOR THE INHIBITION OF HERPESVIRUSES | UNIVERSITé LAVAL (CA) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | NOS3, NOS1, DNA2 | HDAC8 122/4885MMP3 1442/4885PLK1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.