Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657969 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL11450712 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| SCHEMBL3793200 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| SCHEMBL17545521 | 0.78 | NOS3 (0.43) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL3797317 | 0.77 | HSP90AB1 (0.45) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| SCHEMBL3804399 | 0.76 | KDM4E (0.55) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL13964465 | 0.76 | KDM4E (0.46) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL19413644 | 0.73 | GABRA1 (0.34) | ALDH1A1KMT2AKDM4EHPGDHSD17B10 | |
| SCHEMBL11529645 | 0.70 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| SCHEMBL22114185 | 0.70 | CYP2A6 (0.39) | ALDH1A1KMT2AMAPK1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |