⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28652226 | 0.83 | — | — | |
| SCHEMBL172717 | 0.81 | THRB (0.35) | — | |
| SCHEMBL9515382 | 0.77 | THRB (0.30) | — | |
| SCHEMBL11853224 | 0.75 | LMNA (0.36) | — | |
| SCHEMBL4474902 | 0.75 | — | — | |
| SCHEMBL7887123 | 0.75 | THRB (0.40) | — | |
| Monochloroacetal SCHEMBL483679 | 0.73 | — | — | |
| SCHEMBL127172 | 0.72 | — | — | |
| SCHEMBL7781320 | 0.72 | — | — | |
| SCHEMBL18194367 | 0.72 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022792-A1 | SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES | GROSS, PHILIP M. | 2010-01-28 | — | — | US | disclosed |
| EP-2086986-A2 | SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES | Starfire Systems, Inc. (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008033980-A2 | SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES | STARFIRE SYSTEMS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |