⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28020086 | 0.86 | CES2 (0.43) | — | |
| SCHEMBL2458022 | 0.77 | — | — | |
| SCHEMBL29352228 | 0.71 | — | — | |
| SCHEMBL180042 | 0.71 | — | — | |
| Methane SCHEMBL28949904 | 0.69 | CA3 (0.52) | — | |
| Methane SCHEMBL28021409 | 0.69 | CA3 (0.52) | — | |
| SCHEMBL27856362 | 0.69 | CA3 (0.52) | — | |
| Bromide SCHEMBL1682049 | 0.69 | CA3 (0.52) | — | |
| Hydrochloric Acid SCHEMBL1682129 | 0.69 | CA3 (0.52) | — | |
| SCHEMBL9135463 | 0.69 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210894-A1 | Method for producing organic compounds by creating aryllithium intermediates and converting them with electrophiles | Siemens Aktiengesellschaft (DE) | 2010-07-28 | — | — | EP | claimed |
| CN-1322707-A | Producing process for triazole derivant | KANEGAFUCHI CHEMICAL IND (JP) | 2001-11-21 | — | — | CN | claimed |
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | claimed |
| CN-1126987-A | Process for producing triazole derivative | KANEGAFUCHI CHEMICAL IND (JP) | 1996-07-17 | — | — | CN | claimed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | claimed |
| EP-2956459-B1 | SUBSTITUTED PHENYL-HEXAHYDROPYRANO[3,4-D][1,3]THIAZIN-2-AMINE COMPOUNDS | PFIZER (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9550795-B2 | Hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | PFIZER INC. (US) | 2017-01-24 | — | — | US | disclosed |
| EP-2751116-B1 | HEXAHYDROPYRANO [3,4-D][1,3]THIAZIN-2-AMINE COMPOUNDS | PFIZER (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9403846-B2 | Carbocyclic- and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | PFIZER INC. (US) | 2016-08-02 | — | — | US | disclosed |
| EP-2852597-B1 | HETEROCYCLIC SUBSTITUTED HEXAHYDROPYRANO [3,4-D][1,3]THIAZIN-2-AMINE COMPOUNDS AS INHIBITORS OF APP, BACE1 AND BACE 2. | PFIZER (US) | 2016-06-08 | — | — | EP | disclosed |
| US-9260455-B2 | Alkyl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | PFIZER INC. (US) | 2016-02-16 | — | — | US | disclosed |
| US-9233981-B1 | Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | PFIZER INC. (US) | 2016-01-12 | — | — | US | disclosed |
| CN-1322707-A | Producing process for triazole derivant | KANEGAFUCHI CHEMICAL IND (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1120397-A2 | Process for preparing triazole derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-08-01 | — | — | EP | disclosed |
| EP-0704419-B1 | PROCESS FOR PRODUCING AN OPTICALLY ACTIVE 2-ARYL-3-ACYLOXY-1,2-PROPANEDIOL | KANEGAFUCHI CHEMICAL IND (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6046354-A | CHEMICAL INTERMEDIATES, E.G. 2-ARYL-1,3-DIACYLOXY-2-PROPANOL, FOR DRUGS AND FUNGICIDES,E.G. (R)-2-(2,4-DIFLUOROPHENYL)-3-(1H-1,2,4-TRIAZOLE-1-YL)-PROPANE-1,2-DIOL, | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-04-04 | — | — | US | disclosed |
| US-5840553-A | OPTICALLY ACTIVE 2-ARYL-3-ACYLOXY-1,2,-PROPANE DIOL USING A MICROORGANISM OR ENZYME DERIVED FROM PORCINE PANCREAS; VIA STEREOSPECIFIC HYDROLYSIS OF A 2-ARYL-1,3-DIACYLOXY-2-PROPANOL; SYNTHETIC CHEMICAL INTERMEDIATES, FUNGICIDES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5654472-A | OPTICALLY PURE 2-ARYL-3-ACYLOXY-1,2-PROPANEDIOL COMPOUNDS; CHEMICAL INTERMEDIATES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| CN-1126987-A | Process for producing triazole derivative | KANEGAFUCHI CHEMICAL IND (JP) | 1996-07-17 | — | — | CN | disclosed |
| EP-0704419-A1 | PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-03 | — | — | EP | disclosed |