Fluoride

Fluoride

SCHEMBL3800073

F.F.F.F.F.Fc1cc(F)c([S])c(F)c1F.Fc1cc(F)c([S])c(F)c1F.Fc1cc(F)c([S])c(F)c1F.Fc1cc(F)c([S])c(F)c1F.Fc1cc(F)c([S])c(F)c1F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA4 P22748 2/20 0.33
CA12 O43570 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL3800080 1.00 CA1 (0.33) CA1CA2CA4CA12CA7
Hydrochloric Acid SCHEMBL3792795 0.97 CA1 (0.32) CA1CA2CA4CA12CA7
Fluoride SCHEMBL3791538 0.81 CA1 (0.36) CA1CA2CA4CA12CA7
Fluoride SCHEMBL3791540 0.81 CA1 (0.36) CA1CA2CA4CA12CA7
Hydrochloric Acid SCHEMBL3795306 0.79 CA1 (0.35) CA1CA2CA4CA12CA7
SCHEMBL5286761 0.78 CA1 (0.38) CA1CA2CA4CA12CA7
Fluoride SCHEMBL943220 0.76 GRIN2D (0.35)
SCHEMBL7702552 0.73 CA1 (0.43) CA1CA2CA4CA12CA7
SCHEMBL41646 0.73 CA1 (0.43) CA1CA2CA4CA12CA7
Fluoride SCHEMBL943552 0.71 CES2 (0.31) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US claimed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 US claimed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US claimed
EP-2137144-B1 PROCESS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES UBE INDUSTRIES (JP) 2013-07-31 EP disclosed
US-8399720-B2 Methods for producing fluorinated phenylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2013-03-19 US disclosed
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130790-A1 Methods for Producing Fluorinated Phenylsulfur Pentafluorides BRPF1, SFXN3, SLFN12 CA1 2757/4885CA2 4248/4885CA4 3007/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA CA1 2632/4885CA2 3338/4885CA4 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.