Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527735 | 0.69 | LMNA (0.42) | GAAMAPTLMNABLMMEN1 | |
| SCHEMBL6071126 | 0.69 | GAA (0.40) | GAAMAPTLMNABLMKMT2A | |
| SCHEMBL11799039 | 0.68 | AKR1C1 (0.40) | GAAMAPTLMNABLMSIGMAR1 | |
| SCHEMBL13378149 | 0.66 | MME (0.44) | LMNAALDH1A1MEN1POLBKMT2A | |
| SCHEMBL15773061 | 0.66 | KDM1A (0.38) | SIGMAR1PRCP | |
| SCHEMBL8410307 | 0.66 | HDAC9 (0.44) | GAAMAPT | |
| SCHEMBL8409829 | 0.65 | MAOB (0.40) | GAAMAPTLMNABLMALDH1A1 | |
| SCHEMBL8061057 | 0.64 | HTR2A (0.39) | ALDH1A1MEN1POLBKMT2ASIGMAR1 | |
| SCHEMBL11244360 | 0.64 | LMNA (0.41) | LMNAALDH1A1MEN1POLBKMT2A | |
| SCHEMBL30715059 | 0.64 | GAA (0.35) | GAAMAPTLMNABLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |