Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306308 | 0.81 | EPHX2 (0.37) | GAAMAPTLMNABLM | |
| SCHEMBL6716719 | 0.81 | EPHX2 (0.37) | GAAMAPTLMNABLM | |
| SCHEMBL6716717 | 0.81 | EPHX2 (0.37) | GAAMAPTLMNABLM | |
| SCHEMBL6690927 | 0.76 | GRM2 (0.41) | LMNABLM | |
| SCHEMBL7737636 | 0.76 | SIGMAR1 (0.37) | LMNABLM | |
| SCHEMBL11799039 | 0.75 | AKR1C1 (0.40) | GAAMAPTLMNABLMSMN1; SMN2 | |
| SCHEMBL9527735 | 0.73 | LMNA (0.42) | GAAMAPTLMNABLMKMT2A | |
| SCHEMBL7346477 | 0.72 | KDM1A (0.38) | LMNATDP1 | |
| SCHEMBL4012265 | 0.72 | HTR2A (0.42) | LMNATDP1 | |
| SCHEMBL8409829 | 0.72 | MAOB (0.40) | GAAMAPTLMNABLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034055-B1 | 2-aminoindane analogs | PRESCIENT NEUROPHARMA INC. (CA) | 2006-04-25 | — | — | US | disclosed |
| US-6699909-B1 | MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS | PRESCIENT NEUROPHARMA INC. (CA) | 2004-03-02 | — | — | US | disclosed |