SCHEMBL3800596

SCHEMBL3800596

CCOP(=O)(O)CC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1OC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
P2RY12 Q9H244 10/20 0.45
P2RY2 P41231 2/20 0.45
P2RY1 P47900 1/20 0.45
P2RY6 Q15077 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
DNPH1 O43598 2/20 0.42
P2RX3 P56373 2/20 0.42
P2RX4 Q99571 2/20 0.42
P2RX2 Q9UBL9 2/20 0.42
NT5E P21589 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3800593 0.90 PRMT6 (0.47) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL3802124 0.89 P2RY12 (0.54) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL13020577 0.89 PRMT6 (0.49) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL1070322 0.87 PRMT6 (0.47) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL13020575 0.87 MEN1 (0.50) P2RY12PRMT6
SCHEMBL26112399 0.86 PRMT6 (0.48) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL3801831 0.84 PRMT6 (0.43) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL26653470 0.84 PRMT6 (0.49) P2RY12PRMT6
SCHEMBL23499895 0.83 PRMT6 (0.49) P2RY12P2RY2P2RY1P2RY6PRMT6
SCHEMBL26653893 0.83 PRMT6 (0.49) P2RY12P2RY2P2RY1P2RY6PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100331397-A1 2-5A ANALOGS AND THEIR METHODS OF USE ALIOS BIOPHARMA, INC. (US) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331397-A1 2-5A ANALOGS AND THEIR METHODS OF USE RNASEL, RNASE1, RNASEH1 P2RY12 4292/4885P2RY2 2712/4885P2RY1 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.