Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.41 |
| ▸ | TET3 | O43151 | 2/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078226 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL7078225 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL7078228 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL22769505 | 0.76 | GRIK1 (0.50) | — | |
| SCHEMBL8353811 | 0.76 | GRIK1 (0.50) | — | |
| SCHEMBL14344224 | 0.76 | GRIK1 (0.50) | — | |
| SCHEMBL9438438 | 0.74 | GRIK1 (0.48) | — | |
| SCHEMBL18766394 | 0.73 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EALDH1A1CRBN | |
| SCHEMBL18057552 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL25660993 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8454986-B2 | Silver nanoparticles with specific surface area and a method for producing them | JANSSEN PHARMACEUTICA N.V. (BE) | 2013-06-04 | — | — | US | disclosed |
| CN-101977509-A | Silver nanoparticles with specific surface area and a method for producing them | JANSSEN PHARMACEUTICA NV | 2011-02-16 | — | — | CN | disclosed |
| US-20100272770-A1 | SILVER NANOPARTICLES WITH SPECIFIC SURFACE AREA AND A METHOD FOR PRODUCING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-10-28 | — | — | US | disclosed |
| EP-2224815-A1 | SILVER NANOPARTICLES WITH SPECIFIC SURFACE AREA AND A METHOD FOR PRODUCING THEM | Janssen Pharmaceutica N.V. (BE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009087122-A1 | SILVER NANOPARTICLES WITH SPECIFIC SURFACE AREA AND A METHOD FOR PRODUCING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272770-A1 | SILVER NANOPARTICLES WITH SPECIFIC SURFACE AREA AND A METHOD FOR PRODUCING THEM | ARG1, BET1, SOD1 | SMN1; SMN2 4198/4885TET2 313/4885TET3 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.