Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221581 | 0.80 | PKM (0.63) | ALDH1A1RAB9APKMLMNASMN1; SMN2 | |
| SCHEMBL3801000 | 0.76 | RAB9A (0.52) | ALDH1A1RAB9APKMLMNASMN1; SMN2 | |
| SCHEMBL5312758 | 0.71 | LTA4H (0.70) | ALDH1A1KMT2ALMNASMN1; SMN2GAA | |
| SCHEMBL15462062 | 0.69 | MAPT (0.67) | RAB9APKMKMT2ALMNASMN1; SMN2 | |
| SCHEMBL3801005 | 0.68 | PKM (0.59) | ALDH1A1RAB9APKMKMT2ALMNA | |
| SCHEMBL5309852 | 0.68 | LTA4H (0.71) | ALDH1A1PKMKMT2ALMNASMN1; SMN2 | |
| SCHEMBL1617605 | 0.68 | MAPT (0.69) | ALDH1A1PKMKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9597683 | 0.68 | RAB9A (0.73) | ALDH1A1RAB9APKMKMT2ALMNA | |
| SCHEMBL17175752 | 0.68 | KMT2A (0.73) | ALDH1A1RAB9APKMKMT2AMEN1 | |
| SCHEMBL9597306 | 0.67 | PKM (0.71) | ALDH1A1RAB9APKMKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842696-B2 | Piperazine derivatives as inhibitors of stearoyl-CoA desaturase | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-30 | — | — | US | claimed |