Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6400918 | 0.82 | FFAR3 (0.32) | TDP1 | |
| SCHEMBL6441211 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL7212483 | 0.80 | CA1 (0.38) | — | |
| SCHEMBL8668420 | 0.79 | CHRM1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12172541 | 0.76 | CYP3A4 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL13077857 | 0.76 | CYP3A4 (0.33) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9577911 | 0.73 | CA2 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL2355142 | 0.73 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL27829186 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1 | |
| SCHEMBL29038756 | 0.71 | TSHR (0.35) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120128745-A1 | BENZYLIDENE MALONATES | BASF SE (DE) | 2012-05-24 | — | — | US | disclosed |
| WO-2010136360-A2 | BENZYLIDENE MALONATES | BASF SE (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120128745-A1 | BENZYLIDENE MALONATES | TERT, REL, MGMT | ALDH1A1 46/4885TSHR 385/4885TDP1 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.