SCHEMBL38016

SCHEMBL38016

[CH2]C(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
TSHR P16473 1/20 0.50
HTR2A P28223 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
CYP2D6 P10635 1/20 0.43
SRC P12931 1/20 0.43
LMNA P02545 2/20 0.41
HRH1 P35367 1/20 0.41
MTOR P42345 1/20 0.41
RAB9A P51151 1/20 0.41
GRM7 Q14831 1/20 0.41
MAPK1 P28482 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MIF P14174 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995862 0.96 DPP4 (0.47) DPP4F2TSHRHTR2ATAAR1
SCHEMBL4076934 0.83 SLC6A3 (0.68) SLC6A2SLC6A4SLC6A3
SCHEMBL4068746 0.83 LMNA (0.50) TSHRLMNASLC6A3
SCHEMBL9180910 0.83 IDO1 (0.54) LMNAMTORRAB9ASLC6A2SLC6A3
SCHEMBL8366103 0.83 TSHR (0.50) DPP4F2TSHRHTR2ATAAR1
SCHEMBL2122133 0.83 LMNA (0.43) DPP4LMNA
SCHEMBL7864100 0.83 LMNA (0.50) TSHRLMNASLC6A3
SCHEMBL2124049 0.83 IDO1 (0.56) TSHRCYP2D6LMNAMAPK1SLC6A2
SCHEMBL832620 0.81
SCHEMBL7940847 0.81 DPP4 (0.47) DPP4F2TSHRHTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7119 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380920-A1 INHIBITORS FOR CORONAVIRUSES Cocrystal Pharma, Inc. (US) 2024-06-12 EP claimed
WO-2024022413-A1 DIVALENT METAL COMPLEX, PREPARATION METHOD THEREFOR AND USE THEREOF, AND ORGANIC OPTOELECTRONIC DEVICE 中国石油化工股份有限公司 2024-02-01 WO claimed
CN-117466944-A Divalent metal complex, preparation method and application thereof, and organic photoelectric device 中国石油化工股份有限公司 2024-01-30 CN claimed
CN-115279875-B Grease composition 出光兴产株式会社 2024-01-12 CN claimed
US-20230357488-A1 CURABLE RESIN COMPOSITION CANON KK (JP) 2023-11-09 US claimed
CN-116547321-A Photopolymerizable composition, optical member formed therefrom, and display device 株式会社东进世美肯 2023-08-04 CN claimed
CN-113490734-B Grease composition 出光兴产株式会社 2023-08-01 CN claimed
CN-113490733-B Grease composition, and method and device for lubricating sliding mechanism using same 出光兴产株式会社 2023-07-28 CN claimed
CN-113508171-B Grease composition 出光兴产株式会社 2023-06-06 CN claimed
CN-116178223-A Preparation method of Belzutifan and intermediate thereof 上海皓鸿生物医药科技有限公司 2023-05-30 CN claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed
US-4308399-A O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1981-12-29 US claimed
US-4298741-A DETHIAPENICILLIN ANTIBIOTICS MERCK & CO., INC. (US) 1981-11-03 US claimed
US-4297488-A 7-α-Methoxy cephalosporins MERCK & CO., INC. (US) 1981-10-27 US claimed
US-4258040-A Cephalosporin compounds MERCK & CO., INC. (US) 1981-03-24 US claimed
EP-0025111-A1 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them SANDOZ AG (CH) 1981-03-18 EP claimed
US-4187220-A New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) 1980-02-05 US claimed
EP-0001644-A1 N-substituted mercaptoacetamidines and pharmaceutical composition containing the same MERCK & CO. INC. (US) 1979-05-02 EP claimed
US-4144271-A IMMUNOREGULANTS MERCK & CO., INC. (US) 1979-03-13 US claimed
US-4060687-A Cephalosporins having a 3-α substituted alkyl grouping MERCK & CO., INC. (US) 1977-11-29 US claimed