Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178909 | 0.92 | MAPT (0.50) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| SCHEMBL38016 | 0.83 | DPP4 (0.50) | TSHRTAAR1DPP4F2RAB9A | |
| SCHEMBL3688628 | 0.81 | TSHR (0.53) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| SCHEMBL133754 | 0.81 | TSHR (0.53) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| SCHEMBL28995862 | 0.80 | DPP4 (0.47) | TSHRTAAR1DPP4F2RAB9A | |
| SCHEMBL1032680 | 0.79 | DPP4 (0.50) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| SCHEMBL15753884 | 0.78 | ALDH1A1 (0.64) | TSHRCYP3A4TDP1MAPTMAOA | |
| SCHEMBL4672030 | 0.77 | TSHR (0.48) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| SCHEMBL3020897 | 0.77 | CA1 (0.50) | TSHRCYP3A4TDP1TAAR1HSD17B10 | |
| Isopropylbenzene SCHEMBL29059047 | 0.76 | TSHR (0.53) | TSHRCYP3A4TDP1TAAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999035129-A1 | SUCCINIMIDE DERIVATIVES WHICH INHIBIT RETINOIC ACID METABOLISM | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |