Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068746 | 1.00 | LMNA (0.50) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL3534179 | 0.92 | ACHE (0.50) | LMNAACHETSHRALOX12HPGD | |
| SCHEMBL38016 | 0.83 | DPP4 (0.50) | LMNATSHRSLC6A3 | |
| SCHEMBL4668741 | 0.82 | LMNA (0.48) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL8327671 | 0.81 | LMNA (0.42) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL12199145 | 0.81 | LMNA (0.53) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL3657920 | 0.81 | LMNA (0.53) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL60997 | 0.81 | LMNA (0.53) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL17923689 | 0.81 | LMNA (0.53) | LMNAACHETSHRALOX12SMN1; SMN2 | |
| SCHEMBL28995862 | 0.80 | DPP4 (0.47) | LMNATSHRSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1148047-A2 | Processes for preparing cyclic compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-24 | — | — | EP | disclosed |