Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KYNU | Q16719 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840756 | 0.79 | ANPEP (0.46) | ANPEPENPEPGRM4 | |
| SCHEMBL11775697 | 0.77 | PBRM1 (0.50) | CES2ACHE | |
| SCHEMBL11768399 | 0.75 | CA12 (0.52) | ACHE | |
| SCHEMBL23217892 | 0.73 | PARP1 (0.52) | ACHE | |
| SCHEMBL70367 | 0.72 | CES1 (0.56) | CES2CES1 | |
| SCHEMBL3801676 | 0.71 | CES2 (0.45) | ANPEPENPEPCES2ACHEGRM4 | |
| Hydrogen Sulfide SCHEMBL28313848 | 0.70 | TDP1 (0.54) | CES1 | |
| SCHEMBL6355543 | 0.70 | ACHE (0.44) | CES2ACHE | |
| SCHEMBL396689 | 0.69 | PTPN1 (0.48) | CES2CES1 | |
| SCHEMBL1726058 | 0.69 | GSK3B (0.46) | ANPEPENPEPCES2ACHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139874-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008126665-A2 | ISOXAZOLINE COMPOUNDS AND THEIR USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-23 | — | — | WO | disclosed |