SCHEMBL3802049

SCHEMBL3802049

CCCC(=O)c1nc2c([nH]1)c(=O)n(C)c(=O)n2C

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.61
ALDH1A1 P00352 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
HSD17B10 Q99714 2/20 0.52
CYP3A4 P08684 1/20 0.52
CASP1 P29466 1/20 0.52
CASP7 P55210 1/20 0.52
ADORA2A P29274 2/20 0.49
ADORA1 P30542 2/20 0.49
GAA P10253 3/20 0.46
RXFP1 Q9HBX9 1/20 0.46
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.46
ADORA2B P29275 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5471123 0.80 POLB (0.56) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL3369548 0.80 ADORA2B (0.58) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL515773 0.75 POLB (0.77) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL16029494 0.75 ALDH1A1 (0.56) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL3389758 0.74 ALDH1A1 (0.82) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL3368846 0.74 POLB (0.69) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL9406540 0.74 POLB (0.83) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL340194 0.74 ALDH1A1 (0.69) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL16029596 0.73 POLB (0.49) POLBALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL9844925 0.72 POLB (0.81) POLBALDH1A1CYP1A2CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820402-B2 Immunoassay element FUJI PHOTO FILM CO., LTD. (JP) 2010-10-26 US disclosed
US-20060024770-A1 Immunoassay element FUJI PHOTO FILM CO., LTD. 2006-02-02 US disclosed
EP-1054258-B1 Homogeneous enzyme immunoassay process using second antibody FUJI PHOTO FILM CO LTD (JP) 2005-12-07 EP disclosed
US-20050084953-A1 Immunoassay element FUJI PHOTO FILM CO., LTD. 2005-04-21 US disclosed
US-20030207332-A1 Immunoassay element SAKAINO YOSHIKI (JP) 2003-11-06 US disclosed
EP-0884591-B1 Immunoassay element FUJI PHOTO FILM CO LTD (JP) 2002-01-30 EP disclosed
EP-1054258-A1 Homogeneous enzyme immunoassay process using second antibody FUJI PHOTO FILM CO., LTD. (JP) 2000-11-22 EP disclosed
EP-0884591-A1 Immunoassay element FUJI PHOTO FILM CO., LTD. (JP) 1998-12-16 EP disclosed
US-5569589-A QUANTITATIVE ANALYSIS; CONTAINING A ENZYME-LABELED ANTIBODY FUJI PHOTO FILM CO., LTD. (JP) 1996-10-29 US disclosed
EP-0451848-B1 Immunoassay element and process for immunoassay FUJI PHOTO FILM CO LTD (JP) 1996-08-21 EP disclosed
US-5547848-A DETERMINING CHANGE IN ENZYMATIC ACTIVITY CAUSED BY COMPETITIVE REACTIONS FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
EP-0503459-B1 Immunoassay element and process for immunoassay FUJI PHOTO FILM CO LTD (JP) 1996-06-26 EP disclosed
EP-0503459-A2 Immunoassay element and process for immunoassay FUJI PHOTO FILM CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0451848-A2 Immunoassay element and process for immunoassay FUJI PHOTO FILM CO., LTD. (JP) 1991-10-16 EP disclosed