SCHEMBL380331

SCHEMBL380331

CCOC(OCC)[SiH2]CCCCN(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379493 0.94 SIGMAR1 (0.32) SIGMAR1
SCHEMBL15611803 0.86 KDM4E (0.30)
SCHEMBL3595185 0.86 THRB (0.31)
SCHEMBL379574 0.86 THRB (0.31)
SCHEMBL704023 0.83 THRB (0.38)
SCHEMBL379354 0.82 SIGMAR1 (0.35) SIGMAR1ALDH1A1
SCHEMBL379597 0.82 ALDH1A1 (0.39) ALDH1A1
SCHEMBL16862750 0.82 CHRM2 (0.32)
SCHEMBL15612352 0.82 KDM4E (0.30)
SCHEMBL15612318 0.82 MEN1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2511334-B1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2018-04-25 EP disclosed
EP-2174801-B1 Rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2016-10-19 EP disclosed
US-8800621-B2 Rubber composition and tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-08-12 US disclosed
US-20120283354-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-11-08 US disclosed
EP-2366558-B1 Tire rubber composition and heavy-load tire SUMITOMO RUBBER IND (JP) 2012-10-31 EP disclosed
EP-2511334-A1 TYRE RUBBER COMPOSITION AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2012-10-17 EP disclosed
EP-2366557-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2012-05-23 EP disclosed
US-8163821-B2 Tire rubber composition and heavy-load tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-24 US disclosed
EP-2184317-B1 Rubber composition and tire SUMITOMO RUBBER IND (JP) 2012-04-18 EP disclosed
US-8119721-B2 Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-02-21 US disclosed
US-20110230613-A1 TIRE RUBBER COMPOSITION AND HEAVY-LOAD TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2011-09-22 US disclosed
EP-2366557-A1 Tire rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
EP-2366558-A1 Tire rubber composition and heavy-load tire Sumitomo Rubber Industries, Ltd. (JP) 2011-09-21 EP disclosed
CN-101747538-A Tread rubber composition for studless tire and studless tire SUMITOMO RUBBER IND 2010-06-23 CN disclosed
EP-2196324-A1 Tread rubber composition for studless tire and studless tire Sumitomo Rubber Industries, Ltd. (JP) 2010-06-16 EP disclosed
US-20100144954-A1 TREAD RUBBER COMPOSITION FOR STUDLESS TIRE AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-06-10 US disclosed
EP-2184317-A1 Rubber composition and tire Sumitomo Rubber Industries, Ltd. (JP) 2010-05-12 EP disclosed
US-20100108213-A1 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-05-06 US disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed