Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992127 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL9463221 | 0.77 | TDP1 (0.44) | TDP1ALDH1A1MAOAMAOBCYP1A2 | |
| SCHEMBL7028012 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1MAOAMAOBCYP1A2 | |
| SCHEMBL843553 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1MAOAMAOBCYP1A2 | |
| SCHEMBL1686690 | 0.75 | ALDH1A1 (0.42) | TDP1ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL1686686 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL842483 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1MAOAMAOBCYP1A2 | |
| SCHEMBL16707371 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL1315699 | 0.75 | TDP1 (0.42) | TDP1ALDH1A1KMT2AMAOAMAOB | |
| SCHEMBL2353433 | 0.73 | TDP1 (0.41) | TDP1ALDH1A1KMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149086-B1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | LEK TOVARNA FARMACEVTSKIH (SI) | 2004-05-12 | — | — | EP | claimed |
| US-6509479-B1 | To produce simvastatin | LEK PHARMACEUTICALS D.D. (SI) | 2003-01-21 | — | — | US | claimed |
| US-5650523-A | REACTION IN SOLVENTS TO FORM HYDROXY GROUPS | MERCK & CO., INC. (US) | 1997-07-22 | — | — | US | claimed |
| EP-0444888-B1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO INC (US) | 1995-02-08 | — | — | EP | claimed |
| EP-0444888-A1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | claimed |
| US-20230405155-A1 | NANOPARTICLE, PHOTOACOUSTIC CONTRAST AGENT, PHOTODYNAMIC THERAPY DRUG, AND PHOTOTHERMAL THERAPY DRUG | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-12-21 | — | — | US | disclosed |
| EP-4241846-A1 | NANOPARTICLES, PHOTOACOUSTIC CONTRAST AGENT, PHOTODYNAMIC THERAPEUTIC AGENT, AND PHOTOTHERMAL THERAPEUTIC AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-13 | — | — | EP | disclosed |
| US-11312795-B2 | Transition metal complex for use in or as a catalyst for olefin polymerization | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-04-26 | — | — | US | disclosed |
| CN-110799552-B | Transition metal complexes for use in or as catalysts for olefin polymerization | SABIC环球技术有限责任公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-3442045-B1 | ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME | SUMITOMO CHEMICAL CO (JP) | 2022-01-12 | — | — | EP | disclosed |
| US-11063219-B2 | Organic photoelectric conversion element, and solar cell module and sensor provided with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-07-13 | — | — | US | disclosed |
| US-10854818-B2 | Dendrimer compound and organic luminescent device employing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| EP-1238026-A2 | PIGMENT CONCENTRATES AND METHODS FOR PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| US-20020016256-A1 | Polymerization catalyst | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-07 | — | — | US | disclosed |
| EP-1149086-A1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2001-10-31 | — | — | EP | disclosed |
| WO-2001044387-A2 | PIGMENT CONCENTRATES AND METHODS FOR PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-21 | — | — | WO | disclosed |
| WO-2000046217-A1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | LEK PHARMACEUTICALS AND CHEMICAL COMPANY D.D. (SI) | 2000-08-10 | — | — | WO | disclosed |
| US-5650523-A | REACTION IN SOLVENTS TO FORM HYDROXY GROUPS | MERCK & CO., INC. (US) | 1997-07-22 | — | — | US | disclosed |
| EP-0444888-B1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO INC (US) | 1995-02-08 | — | — | EP | disclosed |
| EP-0444888-A1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230405155-A1 | NANOPARTICLE, PHOTOACOUSTIC CONTRAST AGENT, PHOTODYNAMIC THERAPY DRUG, AND PHOTOTHERMAL THERAPY DRUG | CRY2, RB1, NR2E3 | TDP1 3946/4885ALDH1A1 1168/4885MEN1 1128/4885 |
| US-10854818-B2 | Dendrimer compound and organic luminescent device employing the same | DCUN1D4, DCUN1D1, FLOT1 | TDP1 683/4885ALDH1A1 1176/4885MEN1 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.