SCHEMBL843553

SCHEMBL843553

Cc1ccc(C)c([Si]([NH])(c2cc(C)ccc2C)c2cc(C)ccc2C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP1A2 P05177 4/20 0.38
CYP2A6 P11509 2/20 0.38
TP53 P04637 2/20 0.37
TAAR1 Q96RJ0 1/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 2/20 0.34
HSD17B10 Q99714 2/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9463221 0.77 TDP1 (0.44) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL1686690 0.75 ALDH1A1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL1686686 0.75 TDP1 (0.48) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL16707371 0.75 TDP1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL1315699 0.75 TDP1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL380345 0.75 TDP1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL7028012 0.75 TDP1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL842483 0.75 TDP1 (0.42) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL1313505 0.73 TDP1 (0.41) TDP1ALDH1A1CYP1A2CYP2A6TP53
SCHEMBL2353433 0.73 TDP1 (0.41) TDP1ALDH1A1CYP1A2CYP2A6TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442045-B1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME SUMITOMO CHEMICAL CO (JP) 2022-01-12 EP disclosed
US-11063219-B2 Organic photoelectric conversion element, and solar cell module and sensor provided with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-07-13 US disclosed
US-10777746-B2 Compound and electronic device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-09-15 US disclosed
US-10290809-B2 Macromolecular compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-20190115540-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL MODULE AND SENSOR PROVIDED WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-18 US disclosed
EP-3442045-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR BATTERY MODULE AND SENSOR PROVIDED WITH SAME Sumitomo Chemical Company, Limited (JP) 2019-02-13 EP disclosed
EP-3412696-A1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-12 EP disclosed
EP-1571170-B1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME SUMITOMO CHEMICAL CO (JP) 2018-09-05 EP disclosed
US-20180053868-A1 PHOTOELECTRIC CONVERSION DEVICE HAVING REFLECTION PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-22 US disclosed
US-9735374-B2 Metal complex and light-emitting device containing the metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-15 US disclosed
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-28 US disclosed
EP-2128168-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE Sumitomo Chemical Company, Limited (JP) 2009-12-02 EP disclosed
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20090043064-A1 METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
EP-1932851-A1 METAL COMPLEX, LIGHT-EMITTING MATERIAL, AND LIGHT-EMITTING DEVICE Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-06-12 US disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070051922-A1 Polymer light-emitting material and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-08 US disclosed
EP-1571170-A1 HIGH-MOLECULAR COMPOUNDS AND POLYMER LIGHT EMITTING DEVICES MADE BY USING THE SAME Sumitomo Chemical Company, Limited (JP) 2005-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE CYBA, BCAT1, CRY1 TDP1 3996/4885ALDH1A1 913/4885CYP1A2 574/4885
US-10290809-B2 Macromolecular compound EXOSC4, TRPC6, MRPS22 TDP1 3879/4885ALDH1A1 3653/4885CYP1A2 4239/4885
US-20080138651-A1 Polyanilines; strong fluorescence and large charge transporting properties BRS3, SLC43A1, MRPS23 TDP1 3524/4885ALDH1A1 4281/4885CYP1A2 3318/4885
US-20070063190-A1 Aromatic compound AHR, AR, NR0B1 TDP1 4108/4885ALDH1A1 2082/4885CYP1A2 45/4885
US-20090043064-A1 METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT TIMCC, AP1M1, TXN TDP1 3278/4885ALDH1A1 4395/4885CYP1A2 2469/4885
US-20100019669-A1 METAL COMPLEX, POLYMER COMPOUND AND DEVICE CONTAINING THOSE AP1M1, MRPL21, C1R TDP1 3925/4885ALDH1A1 4138/4885CYP1A2 3212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.