Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807780 | 0.90 | HTR3A (0.41) | ACHEPOLBALDH1A1KDM4E | |
| SCHEMBL3804205 | 0.80 | RAB9A (0.40) | NPC1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3805844 | 0.79 | KDR (0.48) | SYKNPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL3808118 | 0.79 | MAOA (0.32) | MAOA | |
| SCHEMBL1570498 | 0.78 | NPC1 (0.45) | SYKNPC1CNR1CNR2MAOA | |
| SCHEMBL28424129 | 0.77 | NPC1 (0.60) | NPC1MEN1KMT2APOLBRAB9A | |
| SCHEMBL3809961 | 0.75 | CDC7 (0.35) | MAOAALDH1A1KDM4E | |
| SCHEMBL29042014 | 0.73 | KDM4E (0.47) | SYKNPC1MAOAMEN1KMT2A | |
| SCHEMBL15474792 | 0.72 | SYK (0.46) | SYKNPC1MEN1KMT2APOLB | |
| SCHEMBL28431640 | 0.71 | NPC1 (0.52) | NPC1POLBALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234618-A1 | BENZOPYRANS AND ANALOGS AS RHO KINASE INHIBITORS | The Scripps Research Institute (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009079008-A1 | BENZOPYRANS AND ANALOGS AS RHO KINASE INHIBITORS | FENG YANGBO (US) | 2009-06-25 | — | — | WO | disclosed |