Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812570 | 0.93 | LTB4R2 (0.39) | LTB4R2SMN1; SMN2RAB9ANPC1NR1H4 | |
| SCHEMBL3812096 | 0.93 | NR1H4 (0.43) | LTB4R2ATMHSD17B2HSD17B1RAB9A | |
| SCHEMBL3811085 | 0.92 | NR1H4 (0.41) | LTB4R2ATMOPRM1OPRD1RAB9A | |
| SCHEMBL3809448 | 0.91 | LTB4R2 (0.38) | LTB4R2NR1H4 | |
| SCHEMBL3811640 | 0.90 | ALDH1A1 (0.38) | LTB4R2SMN1; SMN2LMNARAB9AALDH1A1 | |
| SCHEMBL3807301 | 0.87 | GSTO1 (0.35) | ATMHSD17B2HSD17B1SMN1; SMN2LMNA | |
| SCHEMBL13715858 | 0.84 | KDM4E (0.43) | LTB4R2ATMOPRM1OPRD1HSD17B2 | |
| SCHEMBL3814871 | 0.84 | LTB4R2 (0.44) | LTB4R2ATMOPRM1OPRD1CPB1 | |
| SCHEMBL3811147 | 0.84 | CPB1 (0.47) | CPB1SMN1; SMN2LMNAMAPTNR1H4 | |
| SCHEMBL3811557 | 0.84 | CPB1 (0.49) | ATMHSD17B2HSD17B1CPB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |