SCHEMBL380753

SCHEMBL380753

CCC(CC)(C(=O)O)C(=O)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
FFAR3 O14843 2/20 0.36
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
NAALAD2 Q9Y3Q0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11373440 0.93 LDHA (0.33) LDHASRRFFAR3MEN1ALDH1A1
SCHEMBL11356460 0.81 LDHA (0.35) LDHASRRFFAR3MEN1ALDH1A1
SCHEMBL28500140 0.81 MEN1 (0.33) MEN1ALDH1A1CYP1A2THRBKMT2A
SCHEMBL13545111 0.79 FFAR3 (0.40) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL7347647 0.78 ALDH1A1 (0.43) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL51201 0.78 FFAR3 (0.41) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL1278535 0.77 ALDH1A1 (0.42) LDHASRRALDH1A1CYP2D6TSHR
SCHEMBL9489101 0.75 FFAR3 (0.39) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL4382923 0.75 FFAR3 (0.39) FFAR3MEN1ALDH1A1CYP1A2THRB
SCHEMBL17818653 0.75 FFAR3 (0.39) FFAR3MEN1ALDH1A1CYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129441-B1 CH-ACID COMPOUNDS AND METAL SALTS AS HARDENER SYSTEM, CORRESPONDING RESIN COMPOSITIONS FOR, AMONGST OTHER THINGS IN FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO KG (DE) 2020-04-29 EP claimed
EP-3129441-A1 CH-ACID COMPOUNDS AND METAL SALTS AS HARDENER SYSTEM, CORRESPONDING RESIN COMPOSITIONS FOR, AMONGST OTHER THINGS IN FASTENING TECHNOLOGY fischerwerke GmbH & Co. KG (DE) 2017-02-15 EP claimed
WO-2015154861-A1 CH-ACID COMPOUNDS AND METAL SALTS AS HARDENER SYSTEM, CORRESPONDING RESIN COMPOSITIONS FOR, AMONGST OTHER THINGS IN FASTENING TECHNOLOGY FISCHERWERKE GMBH & CO. KG (DE) 2015-10-15 WO claimed
US-6136876-A SHRINKAGE INHIBITION AIR PRODUCTS AND CHEMICALS (US) 2000-10-24 US claimed
EP-1002816-A2 Weak bronsted acid derivatives for improving dimensional stability of polyurethane flexible foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-24 EP claimed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP claimed
JP-56015279-A None JP disclosed
EP-4352038-A2 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-04-17 EP disclosed
US-20230372537-A1 LIPID NANOPARTICLE FORMULATIONS ACUITAS THERAPEUTICS INC (CA) 2023-11-23 US disclosed
US-11795301-B2 Fixing systems having fine-particle fillers FISCHERWERKE GMBH & CO. KG (DE) 2023-10-24 US disclosed
WO-2023194122-A1 COMPOUNDS ON THE BASIS OF RECYCLED COMPOUNDS, FOR MULTI-COMPONENT REACTIVE RESIN SYSTEMS FOR CHEMICAL FIXING HILTI AKTIENGESELLSCHAFT (LI) 2023-10-12 WO disclosed
EP-4257570-A1 COMPOUNDS BASED ON RECYCLED COMPOUNDS FOR MULTICOMPONENT REACTIVE RESIN SYSTEMS FOR CHEMICAL FIXATION Hilti Aktiengesellschaft (LI) 2023-10-11 EP disclosed
US-11712481-B2 Lipid nanoparticle formulations Acuitas Therapeutics, Inc. (CA) 2023-08-01 US disclosed
EP-0089393-A1 Process for producing substituted pyrroles ETHYL CORPORATION (US) 1983-09-28 EP disclosed
EP-0089392-A1 Process for producing substituted pyrroles ETHYL CORPORATION (US) 1983-09-28 EP disclosed
US-4374255-A BY REACTION OF A CHLOROMETHYL LOWERALKYL KETONE, A DILOWERALKYL ACETONE DICARBOXYLATES AND AN AMINE IN THE PRESENCE OF A LOWER ALKANOL ETHYL CORPORATION (US) 1983-02-15 US disclosed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP disclosed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP disclosed
EP-0024807-A1 Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1981-03-11 EP disclosed
JP-S5615279-A NOVEL, LACTONE OF OCTANOIC ACIDS SHIONO KORYO KK 1981-02-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11712481-B2 Lipid nanoparticle formulations LIPA, PLIN3, PLIN1 LDHA 1173/4885SRR 2365/4885FFAR3 1305/4885
US-20230372537-A1 LIPID NANOPARTICLE FORMULATIONS LIPA, PLIN3, PLIN1 LDHA 1173/4885SRR 2365/4885FFAR3 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.