Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 2/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911423 | 0.73 | HTR2A (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3810612 | 0.73 | HTR2A (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7141278 | 0.71 | OPRM1 (0.60) | OPRM1MMP1MMP9MMP13CHRM1 | |
| SCHEMBL3724780 | 0.71 | TAS2R14 (0.44) | KCNA5CHRM5CAMK2AMMP1MMP9 | |
| SCHEMBL3635250 | 0.70 | LMNA (0.51) | KCNA5CHRM5CAMK2AMMP1MMP9 | |
| SCHEMBL3634464 | 0.69 | MEN1 (0.47) | KCNA5CHRM5CAMK2AMMP1MMP9 | |
| SCHEMBL3634460 | 0.69 | MEN1 (0.47) | KCNA5CHRM5CAMK2AMMP1MMP9 | |
| SCHEMBL3806319 | 0.69 | CHRM5 (0.36) | KCNA5CHRM5CAMK2AMMP1MMP13 | |
| SCHEMBL3722537 | 0.69 | OPRM1 (0.39) | CHRM5OPRM1CHRM1CHRM3CNR1 | |
| SCHEMBL7141686 | 0.68 | CHRM2 (0.61) | OPRM1MMP1MMP9MMP13CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | claimed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | claimed |