Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911423 | 1.00 | HTR2A (0.33) | HTR2AHTR2CHTR7AGTR2CCR4 | |
| SCHEMBL3724470 | 0.74 | HTR2A (0.37) | HTR2AHTR2CAGTR2KMT2A | |
| SCHEMBL3808873 | 0.73 | KCNA5 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL4814429 | 0.73 | HSD11B1 (0.35) | HTR2AHTR2CCCR3MEN1ALDH1A1 | |
| SCHEMBL3725678 | 0.73 | HSD11B1 (0.35) | HTR2AHTR2CCCR3MEN1ALDH1A1 | |
| SCHEMBL4896395 | 0.71 | OPRK1 (0.33) | HTR2AHTR2CAGTR2MEN1ALDH1A1 | |
| SCHEMBL3802612 | 0.71 | OPRK1 (0.33) | HTR2AHTR2CAGTR2MEN1ALDH1A1 | |
| SCHEMBL3727160 | 0.70 | RORC (0.38) | HTR2AHTR2CAGTR2ALDH1A1 | |
| SCHEMBL3728078 | 0.70 | HTR7 (0.37) | HTR2AHTR2CHTR7MEN1ALDH1A1 | |
| SCHEMBL3723935 | 0.69 | MCL1 (0.39) | HTR2AHTR2CHTR7CCR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |