Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158250 | 0.89 | ENPP2 (0.37) | — | |
| SCHEMBL2158478 | 0.88 | MCHR1 (0.39) | MCHR1NPY1R | |
| SCHEMBL2158448 | 0.86 | NPY1R (0.38) | MCHR1NPY1R | |
| SCHEMBL14865860 | 0.86 | CYP1A2 (0.35) | — | |
| SCHEMBL2158079 | 0.85 | PPARA (0.35) | MCHR1NPY1R | |
| SCHEMBL2157491 | 0.83 | SLC6A2 (0.42) | — | |
| SCHEMBL2157419 | 0.83 | NPY1R (0.36) | MCHR1NPY1R | |
| SCHEMBL2157793 | 0.83 | NPY1R (0.38) | MCHR1NPY1R | |
| SCHEMBL3808991 | 0.83 | SLC6A12 (0.33) | — | |
| SCHEMBL2157549 | 0.82 | P2RX7 (0.40) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123242-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS (CANADA) INCORPORATED (CA) | 2013-05-16 | — | — | US | disclosed |
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123242-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | HAVCR2, ZC3HAV1, MAVS | PDK2 2303/4885MCHR1 3432/4885NPY1R 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.