Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 5/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | PRF1 | P14222 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809704 | 0.93 | MMP2 (0.49) | NPSR1GLO1SLC40A1KDM4EMMP2 | |
| SCHEMBL3810988 | 0.90 | GLO1 (0.48) | NPSR1GLO1SLC40A1KDM4EMMP2 | |
| SCHEMBL3816657 | 0.85 | NPSR1 (0.70) | NPSR1IKBKBKDM4EMAPT | |
| SCHEMBL2158247 | 0.84 | NPSR1 (0.60) | NPSR1GLO1IKBKBSLC40A1KDM4E | |
| SCHEMBL3807312 | 0.81 | NPSR1 (0.53) | NPSR1IKBKBKDM4E | |
| SCHEMBL3811718 | 0.81 | KCNH2 (0.51) | NPSR1IKBKBKDM4E | |
| SCHEMBL3812600 | 0.80 | KCNH2 (0.50) | NPSR1IKBKBKDM4E | |
| SCHEMBL3816532 | 0.79 | NPSR1 (0.69) | NPSR1IKBKBKDM4EMETAP2TP53 | |
| SCHEMBL3816506 | 0.78 | PPARD (0.43) | NPSR1IKBKBKDM4E | |
| SCHEMBL3817321 | 0.78 | NPSR1 (0.49) | NPSR1IKBKBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |