Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | USP8 | P40818 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158015 | 0.85 | NPSR1 (0.49) | PPARDNPSR1ACLYMEN1KMT2A | |
| SCHEMBL3816150 | 0.85 | ACLY (0.55) | NPSR1ACLYMEN1KMT2AKDM4E | |
| SCHEMBL3809704 | 0.82 | MMP2 (0.49) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3816898 | 0.82 | ACLY (0.58) | NPSR1ACLYMEN1KMT2AKDM4E | |
| SCHEMBL3811048 | 0.79 | MCL1 (0.52) | NPSR1ACLYPOLB | |
| SCHEMBL3812325 | 0.79 | MEN1 (0.53) | NPSR1ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL3809711 | 0.78 | NPSR1 (0.52) | NPSR1KDM4EIKBKB | |
| SCHEMBL3811274 | 0.77 | HSD17B2 (0.56) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3816575 | 0.77 | NPSR1 (0.67) | NPSR1ACLYKDM4ERXFP1IKBKB | |
| SCHEMBL3810988 | 0.76 | GLO1 (0.48) | NPSR1ACLYKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |