Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 5/20 | 0.48 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809704 | 0.93 | MMP2 (0.49) | GLO1MMP2NPSR1KDM4EMETAP2 | |
| SCHEMBL3809711 | 0.90 | NPSR1 (0.52) | GLO1MMP2NPSR1KDM4EMETAP2 | |
| SCHEMBL2158020 | 0.84 | ACLY (0.65) | GLO1ACLYMMP2NPSR1 | |
| SCHEMBL3814727 | 0.83 | NPSR1 (0.57) | ACLYNPSR1KDM4E | |
| SCHEMBL3816724 | 0.81 | ACLY (0.47) | ACLYNPSR1 | |
| SCHEMBL3815210 | 0.78 | ITGA1 (0.49) | ACLYNPSR1SLC40A1 | |
| SCHEMBL3809012 | 0.78 | NPSR1 (0.56) | ACLYNPSR1KDM4E | |
| SCHEMBL3809155 | 0.77 | NPSR1 (0.49) | ACLYNPSR1KDM4EMAPT | |
| SCHEMBL3809896 | 0.77 | ACLY (0.53) | ACLYNPSR1KDM4EMETAP2TP53 | |
| SCHEMBL3816592 | 0.77 | TRIM24 (0.46) | ACLYNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |