Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816560 | 0.85 | HSD17B1 (0.44) | HSD17B1HSD17B2LMNANPC1KMT2A | |
| SCHEMBL2249017 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2LMNA | |
| SCHEMBL3811162 | 0.82 | GPBAR1 (0.44) | HPGDSMN1; SMN2MEN1KMT2ASLC6A2 | |
| SCHEMBL3812250 | 0.82 | HPGD (0.41) | HSD17B1HSD17B2NPC1HPGDSMN1; SMN2 | |
| SCHEMBL3811484 | 0.82 | ACLY (0.43) | LMNA | |
| SCHEMBL3811638 | 0.81 | MAPT (0.45) | HSD17B1HSD17B2HPGDMEN1KMT2A | |
| SCHEMBL3807285 | 0.81 | CES2 (0.47) | LMNANPC1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL3817235 | 0.81 | HSD17B1 (0.45) | HSD17B1HSD17B2NPC1HPGDSMN1; SMN2 | |
| SCHEMBL3811062 | 0.80 | HSD17B1 (0.43) | HSD17B1HSD17B2LMNANPC1KMT2A | |
| SCHEMBL3809473 | 0.80 | HSD17B1 (0.49) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |