Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431838 | 0.84 | CASR (0.48) | NR3C1PGRNR3C2CASR | |
| SCHEMBL6668591 | 0.81 | NR3C1 (0.57) | NR3C1ARHRH4PGRNR3C2 | |
| SCHEMBL3826671 | 0.77 | NR3C1 (0.45) | NR3C1PGR | |
| SCHEMBL4432828 | 0.75 | NR3C1 (0.40) | NR3C1ARMEN1KMT2AKLKB1 | |
| SCHEMBL4432825 | 0.74 | NR3C1 (0.44) | NR3C1ARMEN1KMT2AKLKB1 | |
| SCHEMBL3817477 | 0.74 | NR3C1 (0.45) | NR3C1NR3C2 | |
| SCHEMBL3825739 | 0.73 | AAK1 (0.31) | NR3C1NR3C2 | |
| SCHEMBL1931828 | 0.71 | NR3C1 (0.61) | NR3C1ARPGRNR3C2 | |
| SCHEMBL16619194 | 0.71 | NR3C1 (0.45) | NR3C1ARMEN1KMT2AKLKB1 | |
| SCHEMBL30042017 | 0.71 | NR3C1 (0.45) | NR3C1ARMEN1KMT2AKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086921-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | Bausch & Lomb Incorporated (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008060799-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED (US) | 2008-05-22 | — | — | WO | disclosed |