Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PLD2 | O14939 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432825 | 0.82 | NR3C1 (0.44) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL3811096 | 0.75 | NR3C1 (0.42) | NR3C1KLKB1MAP4K1HRH4MEN1 | |
| SCHEMBL22996085 | 0.74 | NR3C1 (0.45) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL16619194 | 0.72 | NR3C1 (0.45) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL30042017 | 0.72 | NR3C1 (0.45) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL3529064 | 0.67 | HRH4 (0.46) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL27713342 | 0.67 | HRH4 (0.44) | NR3C1KLKB1MAP4K1HRH4KDM4E | |
| SCHEMBL6668591 | 0.67 | NR3C1 (0.57) | NR3C1HRH4ARPGRNR3C2 | |
| SCHEMBL27733670 | 0.66 | PPARA (0.48) | HRH4AR | |
| SCHEMBL3525778 | 0.65 | MTNR1A (0.47) | NR3C1KLKB1MAP4K1HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121670-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | Bausch & Lomb Incorporated (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008088969-A2 | SYNTHESIS OF SELECTED STEREOISOMERS OF CERTAIN SUBSTITUTED ALCOHOLS | BAUSCH & LOMB INCORPORATED (US) | 2008-07-24 | — | — | WO | disclosed |