Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807300 | 0.90 | RELA (0.50) | PKMSLC10A6NFKBIARELASMN1; SMN2 | |
| SCHEMBL3809680 | 0.88 | SLC40A1 (0.53) | SLC10A6NFKBIARELASMN1; SMN2MEN1 | |
| SCHEMBL3808919 | 0.84 | NPSR1 (0.48) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3816884 | 0.84 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL3816563 | 0.84 | NPSR1 (0.54) | L3MBTL1CA2HSD17B1HSD17B2SMN1; SMN2 | |
| SCHEMBL3814765 | 0.84 | MEN1 (0.44) | MMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL2158397 | 0.84 | NPSR1 (0.53) | PKMSLC10A6L3MBTL1CA1CA2 | |
| SCHEMBL3816632 | 0.83 | NPSR1 (0.49) | HSD17B1HSD17B2GAAMEN1KMT2A | |
| SCHEMBL3816971 | 0.82 | NPSR1 (0.48) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3816837 | 0.82 | NPSR1 (0.48) | NFKBIARELASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |