Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815168 | 0.91 | NPSR1 (0.54) | IKBKBPOLBNPSR1KDM4ERXFP1 | |
| SCHEMBL3809896 | 0.91 | ACLY (0.53) | ACLYNPSR1KDM4ERXFP1ALDH1A1 | |
| SCHEMBL3814727 | 0.88 | NPSR1 (0.57) | ACLYIKBKBNPSR1KDM4ERXFP1 | |
| SCHEMBL3814654 | 0.84 | ACLY (0.51) | ACLYNPSR1KDM4ERXFP1ALDH1A1 | |
| SCHEMBL2158255 | 0.84 | ACLY (0.73) | ACLYIKBKBNPSR1KDM4ERXFP1 | |
| SCHEMBL3817249 | 0.81 | NPSR1 (0.61) | IKBKBPOLBNPSR1KDM4ERXFP1 | |
| SCHEMBL3815310 | 0.81 | NPSR1 (0.62) | ACLYIKBKBNPSR1KDM4ERXFP1 | |
| SCHEMBL3809822 | 0.80 | ACLY (0.43) | ACLYIKBKBNPSR1ALDH1A1 | |
| SCHEMBL3816575 | 0.80 | NPSR1 (0.67) | ACLYIKBKBNPSR1KDM4ERXFP1 | |
| SCHEMBL3808147 | 0.80 | ALDH1A1 (0.47) | NPSR1KDM4ERXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |