Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 5/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817013 | 0.91 | NPSR1 (0.53) | ACLYNPSR1KDM4ERXFP1STAT3 | |
| SCHEMBL3814727 | 0.87 | NPSR1 (0.57) | ACLYCCR2NPSR1KDM4ERXFP1 | |
| SCHEMBL3809896 | 0.85 | ACLY (0.53) | ACLYNPSR1KDM4ERXFP1FLT1 | |
| SCHEMBL3811534 | 0.84 | ACLY (0.52) | ACLYNPSR1KDM4ERXFP1ALDH1A1 | |
| SCHEMBL2157934 | 0.84 | ACLY (0.72) | ACLYCCR2NPSR1KDM4ERXFP1 | |
| SCHEMBL3812237 | 0.81 | ACLY (0.42) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL3807592 | 0.80 | ALDH1A1 (0.45) | NPSR1KDM4ERXFP1ALDH1A1 | |
| SCHEMBL3816575 | 0.79 | NPSR1 (0.67) | ACLYNPSR1KDM4ERXFP1METAP2 | |
| SCHEMBL3809012 | 0.78 | NPSR1 (0.56) | ACLYCCR2NPSR1KDM4ERXFP1 | |
| SCHEMBL3811715 | 0.77 | NPSR1 (0.69) | NPSR1KDM4ERXFP1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |