Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814874 | 0.90 | LTB4R2 (0.40) | ALDH1A1SMN1; SMN2LTB4R2LMNAMAPT | |
| SCHEMBL3812570 | 0.88 | LTB4R2 (0.39) | SMN1; SMN2LTB4R2RAB9A | |
| SCHEMBL2157703 | 0.87 | LTB4R2 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1LTB4R2 | |
| SCHEMBL3815496 | 0.87 | MEN1 (0.43) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL3809784 | 0.86 | MEN1 (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPK1 | |
| SCHEMBL3811085 | 0.86 | NR1H4 (0.41) | KMT2AMEN1LTB4R2RAB9A | |
| SCHEMBL3809448 | 0.85 | LTB4R2 (0.38) | KMT2AMEN1LTB4R2CCR5 | |
| SCHEMBL3812096 | 0.84 | NR1H4 (0.43) | ALDH1A1KMT2AMEN1LTB4R2RAB9A | |
| SCHEMBL3815444 | 0.84 | MEN1 (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1LTB4R2 | |
| SCHEMBL3807301 | 0.80 | GSTO1 (0.35) | ALDH1A1SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |