Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL381484 | 0.85 | P2RY14 (0.37) | P2RX7HSD11B1DPP4DPP7PLAT | |
| Trifluoroacetic Acid SCHEMBL381532 | 0.85 | PRCP (0.38) | HTR2AHTR2CHSD11B1DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL380865 | 0.84 | S1PR5 (0.38) | P2RX7HSD11B1PLATCHRM3 | |
| Trifluoroacetic Acid SCHEMBL381380 | 0.84 | TP53 (0.39) | P2RX7HSD11B1DPP4DPP7CHRM1 | |
| SCHEMBL13031202 | 0.82 | TP53 (0.42) | P2RX7L3MBTL1TP53 | |
| SCHEMBL380467 | 0.82 | TP53 (0.42) | P2RX7L3MBTL1TP53 | |
| SCHEMBL381546 | 0.82 | LMNA (0.42) | P2RX7HSD11B1DPP4DPP7CYP27A1 | |
| SCHEMBL13031216 | 0.82 | LMNA (0.42) | P2RX7HSD11B1DPP4DPP7CYP27A1 | |
| Trifluoroacetic Acid SCHEMBL381863 | 0.82 | AKR1C2 (0.41) | HTR2CHSD11B1CHRM1CHRM2CHRM5 | |
| Trifluoroacetic Acid SCHEMBL381517 | 0.82 | PAX8 (0.35) | HSD11B1DPP4DPP7UTS2RCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049513-B1 | PIPERIDINYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2012-01-25 | — | — | EP | disclosed |