Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL381532 | 0.94 | PRCP (0.38) | DPP4DPP8DPP7HSD11B1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL381484 | 0.92 | P2RY14 (0.37) | DPP4DPP8DPP7HSD11B1P2RX7 | |
| SCHEMBL13031267 | 0.91 | TP53 (0.46) | TP53HSD11B1CHRM4CHRM2CHRM5 | |
| Trifluoroacetic Acid SCHEMBL381517 | 0.90 | PAX8 (0.35) | DPP4DPP8DPP7HSD11B1SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL381863 | 0.90 | AKR1C2 (0.41) | HSD11B1AKR1C2AKR1C1P2RY14CHRM2 | |
| Trifluoroacetic Acid SCHEMBL380699 | 0.90 | FFAR4 (0.35) | DPP4DPP8DPP7DPP9ATM | |
| Trifluoroacetic Acid SCHEMBL380865 | 0.86 | S1PR5 (0.38) | HSD11B1P2RX7CHRM3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL380667 | 0.86 | RAD52 (0.39) | CHRM2CHRM1CHRM3 | |
| Trifluoroacetic Acid SCHEMBL381002 | 0.86 | L3MBTL1 (0.39) | HSD11B1 | |
| SCHEMBL3564422 | 0.85 | HTR2A (0.43) | TP53HSD11B1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049513-B1 | PIPERIDINYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2012-01-25 | — | — | EP | disclosed |