SCHEMBL38133

SCHEMBL38133

C=Cc1ccc(C(=O)c2ccc(C=C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
TDP1 Q9NUW8 1/20 0.48
SRD5A2 P31213 6/20 0.48
LMNA P02545 3/20 0.48
HPGD P15428 3/20 0.48
MAPT P10636 2/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
PKM P14618 1/20 0.48
HTT P42858 1/20 0.48
TAS1R3 Q7RTX0 2/20 0.46
TAS1R1 Q7RTX1 2/20 0.46
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.39
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39787 0.91 ALDH1A1 (0.61) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL27324591 0.89 SRD5A2 (0.57) ALDH1A1SRD5A2HPGDHTTTSHR
SCHEMBL4900360 0.89 ALDH1A1 (0.67) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL4805920 0.85 RAB9A (0.60) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL31265583 0.84 ALDH1A1 (0.46) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL31265582 0.84 ALDH1A1 (0.46) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL3753579 0.84 ALDH1A1 (0.58) ALDH1A1TDP1TAS1R3TAS1R1TSHR
SCHEMBL4904356 0.84 MAPT (0.59) ALDH1A1LMNAHPGDMAPTPKM
Benzophenone SCHEMBL28767057 0.83 ALDH1A1 (0.64) ALDH1A1TDP1SRD5A2LMNAHPGD
SCHEMBL1089254 0.82 ELANE (0.62) TDP1LMNAMAPTESR1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599752-A Compositions and methods for selective chemical mechanical polishing of oxides CMC材料股份有限公司 2022-06-07 CN claimed
CN-104844908-B A kind of micropore medical air-permeable resistance bacterium material and preparation method thereof 深圳市安保医疗感控科技有限公司 2017-06-20 CN claimed
CN-105051086-A Active polymer polyols and a process for their production BAYER MATERIALSCIENCE LLC 2015-11-11 CN claimed
CN-104844908-A Medical air-permeable and antibacterial microporous material and preparation method for same SAFE SECURE PACKING SHENZHEN CO LTD 2015-08-19 CN claimed
CN-104540864-A Polyurea elastomer having increased chemical resistance BASF SE 2015-04-22 CN claimed
US-20130202531-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2013-08-08 US claimed
CN-1660919-B Process for production of polymer polyols BAYER MATERIALSCIENCE LLC 2012-11-14 CN claimed
EP-2382080-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS Indicator Systems International, Inc. (US) 2011-11-02 EP claimed
US-20110042344-A1 POLYMERIC INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2011-02-24 US claimed
US-20100196636-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. 2010-08-05 US claimed
WO-2009061831-A1 POLYMERIC INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2009-05-14 WO claimed
EP-1893147-A2 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING Indicator Systems International, Inc. (US) 2008-03-05 EP claimed
CN-1914173-A Quinolines useful in treating cardiovascular disease WYETH CORP (US) 2007-02-14 CN claimed
US-20070003606-A1 Apparatus and method for detecting bacterial growth beneath a wound dressing OSRAM SYLVANIA INC. 2007-01-04 US claimed
WO-2006133430-A2 APPARATUS AND METHOD FOR DETECTING BACTERIAL GROWTH BENEATH A WOUND DRESSING INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2006-12-14 WO claimed
CN-1660919-A Process for production of polymer polyols BAYER MATERIALSCIENCE LLC (US) 2005-08-31 CN claimed
CN-1150234-C Novel (co) polymers and novel polymerization processes based on atom (or group) transfer radical polymerization K����ټӴ���˹�� 2004-05-19 CN claimed
EP-0787750-B1 Poly(alkylethylene) structural isomers BOREALIS GMBH (AT) 2003-05-14 EP claimed
US-6149952-A Method for determining deleterious bacterial growth in packaged food utilizing hydrophilic polymers Stoltenberg, Herbert W. (US) 2000-11-21 US claimed
WO-1999059431-A1 METHOD FOR DETERMINING DELETERIOUS BACTERIAL GROWTH IN PACKAGED FOOD UTILIZING HYDROPHILIC POLYMERS THOMAS J. HORAN FAMILY TRUST (US) 1999-11-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100196636-A1 INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS PGLS, MGAM, G6PD ALDH1A1 244/4885TDP1 1492/4885SRD5A2 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.