Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 6/20 | 0.66 |
| ▸ | SCN2A | Q99250 | 6/20 | 0.66 |
| ▸ | SCN3A | Q9NY46 | 6/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109075 | 0.83 | SCN1A (0.72) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| Detanosal SCHEMBL2110875 | 0.83 | SCN1A (0.68) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| SCHEMBL9219907 | 0.82 | ALDH1A1 (0.76) | CHRM1KDM4ELMNAALDH1A1CYP3A4 | |
| Detanosal SCHEMBL30397539 | 0.82 | SCN1A (0.66) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| SCHEMBL4644788 | 0.82 | SCN1A (0.66) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| SCHEMBL21705597 | 0.82 | SCN1A (0.66) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| Detanosal SCHEMBL29163805 | 0.82 | SCN1A (0.66) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| SCHEMBL29155869 | 0.81 | SCN1A (0.64) | SCN1ASCN2ASCN3ACHRM2CHRM3 | |
| SCHEMBL2457943 | 0.80 | TSHR (0.77) | KDM4ECYP2D6LMNACYP1A2ALDH1A1 | |
| SCHEMBL9576565 | 0.79 | SCN1A (0.63) | SCN1ASCN2ASCN3ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO LTD (CN) | 2021-11-18 | — | — | US | claimed |
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353579-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | SCN1A 846/4885SCN2A 918/4885SCN3A 1200/4885 |
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | SCN1A 846/4885SCN2A 918/4885SCN3A 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.