Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381546 | 0.88 | LMNA (0.42) | MCHR1P2RX7LMNAHSD11B1CYP27A1 | |
| SCHEMBL13031216 | 0.88 | LMNA (0.42) | MCHR1P2RX7LMNAHSD11B1CYP27A1 | |
| SCHEMBL381332 | 0.86 | MCHR1 (0.34) | MCHR1HSD11B1SCN9ACHRM3 | |
| SCHEMBL381499 | 0.86 | MCHR1 (0.34) | MCHR1HSD11B1SCN9ACHRM3 | |
| SCHEMBL381134 | 0.85 | CNR1 (0.36) | MCHR1LMNASCN9ACHRM3 | |
| SCHEMBL381812 | 0.84 | CHRM3 (0.33) | HSD11B1CHRM3 | |
| SCHEMBL380490 | 0.84 | AKR1C2 (0.37) | MCHR1SCN9ACHRM3KDM1A | |
| SCHEMBL381541 | 0.83 | MAPT (0.34) | MCHR1LMNAHSD11B1 | |
| SCHEMBL380467 | 0.83 | TP53 (0.42) | P2RX7SCN9ASCN5A | |
| SCHEMBL13031202 | 0.83 | TP53 (0.42) | P2RX7SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049513-B1 | PIPERIDINYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2012-01-25 | — | — | EP | claimed |