Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896943 | 0.86 | SLC6A2 (0.36) | SLC6A2SLC6A4CYP1A2HIF1ASLC6A3 | |
| SCHEMBL5897600 | 0.85 | SLC6A2 (0.38) | SLC6A2SLC6A4CYP1A2HIF1ASLC6A3 | |
| SCHEMBL12333840 | 0.80 | — | — | |
| SCHEMBL1877028 | 0.80 | — | — | |
| SCHEMBL13882832 | 0.79 | CYP1A2 (0.46) | CYP1A2HIF1ASMN1; SMN2BRD4TP53 | |
| SCHEMBL5897643 | 0.78 | SLC6A3 (0.35) | SLC6A4CYP1A2HIF1ASLC6A3ALDH1A1 | |
| SCHEMBL3974812 | 0.75 | CYP1A2 (0.43) | CYP1A2HIF1ASMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL32681696 | 0.75 | KDM4E (0.36) | SLC6A2SLC6A4CYP1A2HIF1ASMN1; SMN2 | |
| SCHEMBL5346726 | 0.72 | CYP1A2 (0.41) | CYP1A2HIF1AKDM4EBRD4TP53 | |
| SCHEMBL3362070 | 0.71 | CYP1A2 (0.38) | SLC6A2SLC6A4CYP1A2HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| US-8278311-B2 | Substituted pyrimidine derivatives | ABBOTT LABORATORIES (US) | 2012-10-02 | — | — | US | disclosed |
| WO-2009134726-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-11-05 | — | — | WO | disclosed |
| US-20090270364-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES | ABBOTT LABORATORIES (US) | 2009-10-29 | — | — | US | disclosed |
| US-7038087-B2 | Process for the production of optically active amino alcohols | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20040063999-A1 | Process for the production of optically active amino alcohols | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1398310-A1 | Process for the production of optically active amino alcohols | Takasago International Corporation (JP) | 2004-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270364-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES | DPYD, TYMP, TYMS | SLC6A2 2699/4885SLC6A4 2239/4885CYP1A2 1101/4885 |
| US-20040063999-A1 | Process for the production of optically active amino alcohols | ADH1C, ADH1A, ADH5 | SLC6A2 1886/4885SLC6A4 627/4885CYP1A2 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.