SCHEMBL3813740

SCHEMBL3813740

Cc1cn([C@H]2CC[C@@H](CO)O2)c(=O)n(N=[N+]=[N-])c1=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
TSHR P16473 2/20 0.41
TK1 P04183 2/20 0.41
ALB P02768 2/20 0.41
PKM P14618 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
ABL1 P00519 1/20 0.34
RIN1 Q13671 1/20 0.34
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9086402 0.97 TK1 (0.39) LMNATSHRTK1ALBPKM
SCHEMBL6757643 0.89 LMNA (0.36) LMNATSHRTK1ALBPKM
SCHEMBL6757641 0.89 LMNA (0.36) LMNATSHRTK1ALBPKM
SCHEMBL10481880 0.87 LMNA (0.37) LMNATSHRTK1ALBPKM
SCHEMBL10481879 0.87 LMNA (0.37) LMNATSHRTK1ALBPKM
SCHEMBL9279551 0.85 TK1 (0.44) LMNATSHRTK1ALBPKM
SCHEMBL10764308 0.84 LMNA (0.35) LMNATSHRTK1ALBPKM
SCHEMBL18258987 0.84 LMNA (0.32) LMNATSHRTK1ALBPKM
SCHEMBL1128956 0.81 TK1 (0.48) LMNATSHRTK1ALBPKM
SCHEMBL1128958 0.81 TK1 (0.48) LMNATSHRTK1ALBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616135-A Subcellular resolution space-time resolved transcriptome 布罗德研究所股份有限公司 2024-02-27 CN claimed
CN-112672764-A Conjugates 格莱科斯生物医药公司 2021-04-16 CN claimed
EP-3230455-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2017-10-18 EP claimed
US-9441227-B2 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA CITY OF HOPE (US) 2016-09-13 US claimed
WO-2016092041-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTIONS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2016-06-16 WO claimed
CN-1768075-A Methods and compositions using suramin, pentosan polysulfate, telomerase antisense, and telomerase inhibitors AU JESSIE L S (US) 2006-05-03 CN claimed
WO-2004070044-A1 BIOLOGICALLY-ACTIVE-MOLECULE-ENRICHED PHOTOSYNTHETIC MICRO-ORGANISMS, PREPARATION METHOD THEREOF AND USES OF SAME BRUNEAU FRANCOIS (FR) 2004-08-19 WO claimed
JP-2002502875-A 2002-01-29 JP claimed
EP-1061922-A1 USE OF $i(N)-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS G.D. SEARLE & CO. (US) 2000-12-27 EP claimed
WO-1999040916-A1 USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS G.D. SEARLE & CO. (US) 1999-08-19 WO claimed
US-5744592-A IMPROVING THE BIOAVAILABILITY AND ABSORPTION OF A DRUG THROUGH THE DIGESTIVE TRACT BY COVALENTLY BONDING THE DRUG AND A 1-O-OR-S-ALKYL-SN-GLYCERO-3-PHOSPHATE NEXSTAR PHARMACEUTICALS, INC. (US) 1998-04-28 US claimed
US-5721241-A PYRIMIDINE COMPOUND USEFUL TO DISRUPT VIRAL, CANCER, FUNGAL, PARASITE OR BACTERIAL REPLICATION AND DIHYDROURACIL DEHYDROGENASE OR URIDINE PHOSPHORYLASE INHIBITORS el Kouni, Mahmoud H. (US) 1998-02-24 US claimed
US-5571798-A TREATMENT OF RETROVIRUS WITH 3-FLUORO-3'-DEOXYTHYMIDINE AND AZIDO DERIVATIVES MEDIVIR AB (SE) 1996-11-05 US claimed
WO-1994016563-A1 1,2-DITHIOLE-3-THIONES FOR THE TREATMENT OF REVERSE TRANSCRIPTASE-DEPENDENT VIRAL INFECTIONS SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1994-08-04 WO claimed
WO-1993016388-A1 METHOD OF DETECTING AND MONITORING LEVELS OF 3'-AMINO-3'-DEOXYTHYMIDINE IN BODY FLUIDS AND ANTIBODIES FOR SAME THE UAB RESEARCH FOUNDATION (US) 1993-08-19 WO claimed
WO-1992017485-A1 PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS EMORY UNIVERSITY (US) 1992-10-15 WO claimed
CN-107898790-B Antiviral JAK inhibitors for the treatment or prevention of retroviral and other viral infections 埃默里大学 2024-06-21 CN disclosed
CN-111630183-B Clear cell renal cell carcinoma biomarker 新加坡科技研究局 2024-06-18 CN disclosed
EP-0250234-A1 Use of specific immunomodulators in treating HIV-induced immunodeficiencies NEWTHERAPEUTICS LIMITED (GB) 1987-12-23 EP disclosed
EP-0217580-A2 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1987-04-08 EP disclosed