Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TK1 | P04183 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757641 | 1.00 | LMNA (0.36) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL3813740 | 0.89 | LMNA (0.41) | LMNAALBALDH1A1MAPK1TSHR | |
| Phosphoric Acid SCHEMBL9086402 | 0.86 | TK1 (0.39) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL10481880 | 0.85 | LMNA (0.37) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL10481879 | 0.85 | LMNA (0.37) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL10764308 | 0.83 | LMNA (0.35) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL10522154 | 0.79 | ALDH1A1 (0.40) | LMNAALBALDH1A1MAPK1TK1 | |
| SCHEMBL6744346 | 0.78 | ABL1 (0.41) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL6744345 | 0.78 | ABL1 (0.41) | LMNAALBALDH1A1MAPK1TSHR | |
| SCHEMBL9279551 | 0.74 | TK1 (0.44) | LMNAALBTSHRTK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480638-A2 | PORPHYRINS WITH VIRUCIDAL ACTIVITY | EMORY UNIVERSITY (US) | 2004-12-01 | — | — | EP | claimed |
| WO-2003057176-A2 | PORPHYRINS WITH VIRUCIDAL ACTIVITY | EMORY UNIVERSITY (US) | 2003-07-17 | — | — | WO | claimed |