Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TK1 | P04183 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3813740 | 0.84 | LMNA (0.41) | LMNATSHRTK1ALBPKM | |
| Phosphoric Acid SCHEMBL9086402 | 0.82 | TK1 (0.39) | LMNATSHRTK1ALBPKM | |
| SCHEMBL9279551 | 0.79 | TK1 (0.44) | LMNATSHRTK1ALBPKM | |
| SCHEMBL7595956 | 0.76 | — | — | |
| SCHEMBL8692891 | 0.75 | POLB (0.51) | TK1 | |
| SCHEMBL1128956 | 0.75 | TK1 (0.48) | LMNATSHRTK1ALBPKM | |
| SCHEMBL1128958 | 0.75 | TK1 (0.48) | LMNATSHRTK1ALBPKM | |
| SCHEMBL6538817 | 0.74 | POLB (0.36) | LMNATSHRTK1ALBPKM | |
| SCHEMBL6757641 | 0.73 | LMNA (0.36) | LMNATSHRTK1ALBPKM | |
| SCHEMBL6757643 | 0.73 | LMNA (0.36) | LMNATSHRTK1ALBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256133-B1 | Bioconjugation of macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-2319854-B1 | Bioconjugation Of Macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-11-30 | — | — | EP | disclosed |