Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.52 |
| ▸ | FAP | Q12884 | 2/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817152 | 0.91 | OPRM1 (0.61) | OPRM1OPRD1OPRK1F2 | |
| SCHEMBL29944964 | 0.82 | OPRM1 (0.61) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3812784 | 0.81 | POLB (0.48) | — | |
| SCHEMBL19387871 | 0.81 | OPRM1 (0.58) | OPRM1OPRD1OPRK1 | |
| SCHEMBL27781840 | 0.79 | POLB (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL2388728 | 0.79 | POLB (0.46) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL3808351 | 0.79 | STAT3 (0.48) | OPRM1 | |
| SCHEMBL3812839 | 0.79 | OPRM1 (0.62) | OPRM1OPRD1OPRK1 | |
| SCHEMBL1372346 | 0.78 | OPRM1 (0.57) | OPRM1OPRD1OPRK1 | |
| SCHEMBL1372320 | 0.78 | OPRM1 (0.57) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086993-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | Zedira GmbH (DE) | 2009-08-12 | — | — | EP | claimed |
| WO-2008055488-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | ZEDIRA GMBH (DE) | 2008-05-15 | — | — | WO | claimed |
| EP-2086993-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | Zedira GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008055488-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | ZEDIRA GMBH (DE) | 2008-05-15 | — | — | WO | disclosed |