Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNE | Q9Y223 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 5/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812287 | 0.77 | CYP19A1 (0.33) | KIT | |
| SCHEMBL1379427 | 0.76 | NPSR1 (0.47) | KITADORA2BMEN1KMT2A | |
| SCHEMBL3814663 | 0.76 | BACE1 (0.33) | KIT | |
| SCHEMBL1381052 | 0.75 | GRM5 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL1379181 | 0.75 | PTGER2 (0.36) | — | |
| SCHEMBL1379534 | 0.75 | PTGER2 (0.36) | — | |
| SCHEMBL3816707 | 0.73 | PTGS2 (0.32) | — | |
| SCHEMBL27422387 | 0.73 | GNE (0.60) | GNEKCNK3KCNK9ALDH1A1MEN1 | |
| SCHEMBL1381518 | 0.72 | KCNA5 (0.37) | KMT2A | |
| SCHEMBL1379821 | 0.72 | NUDT1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776355-A4 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1776355-A2 | POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006014877-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |