Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216800 | 0.85 | CA1 (0.60) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL3780795 | 0.84 | HPGD (0.58) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL3814770 | 0.83 | ABL1 (0.59) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL9653150 | 0.82 | ALDH1A1 (0.60) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL5467371 | 0.82 | ABL1 (0.46) | PDK2PDK4ALDH1A1MAPTMEN1 | |
| SCHEMBL824683 | 0.81 | HPGD (0.51) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL11576641 | 0.80 | PDK2 (0.68) | HPGDPDK2PDK4ALDH1A1MAPT | |
| SCHEMBL1504203 | 0.79 | HPGD (0.54) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL16098644 | 0.79 | ALDH1A1 (0.54) | HPGDHTTALDH1A1MAPTMEN1 | |
| SCHEMBL6585743 | 0.78 | ALOX15 (0.52) | HPGDHTTPDK2PDK4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524855-B2 | Selected benzofuran derivatives | ARPIDA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| US-20080108610-A1 | Selected Benzofuran Derivatives | ARPIDA AG (CH) | 2008-05-08 | — | — | US | disclosed |
| EP-1838704-A1 | SELECTED BENZOFURAN DERIVATIVES | Arpida AG (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006072370-A1 | SELECTED BENZOFURAN DERIVATIVES | ARPIDA AG (CH) | 2006-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108610-A1 | Selected Benzofuran Derivatives | ABCG2, BPTF, SBDS | HPGD 311/4885HTT 2085/4885PDK2 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.