SCHEMBL3814404

SCHEMBL3814404

CCCCCCO[Si](OCCCCCC)OCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 2/20 0.47
NAAA Q02083 1/20 0.46
CES2 O00748 1/20 0.44
EPHX1 P07099 1/20 0.43
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.42
LPAR3 Q9UBY5 5/20 0.41
LPAR2 Q9HBW0 4/20 0.41
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA9 Q16790 4/20 0.41
LPAR1 Q92633 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23365026 1.00 TSHR (0.47) TSHRTHRBNAAACES2EPHX1
SCHEMBL23365060 1.00 TSHR (0.47) TSHRTHRBNAAACES2EPHX1
SCHEMBL17965931 0.97 NAAA (0.42) TSHRTHRBNAAACES2EPHX1
SCHEMBL28200062 0.89 NAAA (0.38) TSHRTHRBNAAACES2EPHX1
SCHEMBL339180 0.88 ADRB2 (0.45) TSHRTHRBNAAACES2CA1
Hydrochloric Acid SCHEMBL9709358 0.85 ADRB2 (0.43) TSHRTHRBNAAACES2CA1
SCHEMBL21812049 0.82 ADRB2 (0.41) TSHRTHRBNAAACES2CA1
SCHEMBL5057904 0.81 NAAA (0.38) TSHRTHRBNAAACES2EPHX1
SCHEMBL28664108 0.80 THRB (0.44) TSHRTHRBNAAACES2MEN1
SCHEMBL29287880 0.80 THRB (0.44) TSHRTHRBNAAACES2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024122620-A1 EYEGLASS LENS ホヤ レンズ タイランド リミテッド 2024-06-13 WO disclosed
CN-118043728-A Spectacle lens, stain-proofing agent composition, and method for producing spectacle lens 豪雅镜片泰国有限公司 2024-05-14 CN disclosed
CN-118043729-A Spectacle lens, stain-proofing agent composition, and method for producing spectacle lens 豪雅镜片泰国有限公司 2024-05-14 CN disclosed
WO-2023054433-A1 EYEGLASS LENS, ANTIFOULING AGENT COMPOSITION, AND METHOD FOR MANUFACTURING EYEGLASS LENS ホヤ レンズ タイランド リミテッド 2023-04-06 WO disclosed
WO-2023054434-A1 LENS FOR EYEWEAR, ANTIFOULING AGENT COMPOSITION, AND METHOD FOR PRODUCING LENS FOR EYEWEAR ホヤ レンズ タイランド リミテッド 2023-04-06 WO disclosed
US-20220403056-A1 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-12-22 US disclosed
EP-4058487-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2022-09-21 EP disclosed
WO-2021097455-A2 CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS BRIDGESTONE CORPORATION (JP) 2021-05-20 WO disclosed
US-20090036687-A1 MULTINUCLEAR COMPLEX AND CONDENSATION PRODUCT THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036687-A1 MULTINUCLEAR COMPLEX AND CONDENSATION PRODUCT THEREOF MNS1, PICALM, NCAPD2 TSHR 3776/4885THRB 4338/4885NAAA 4149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.