Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 8/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815360 | 0.96 | KDM4E (0.38) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL3812444 | 0.91 | ALDH1A1 (0.36) | HSD17B1HSD17B2MAPTNPSR1CNR2 | |
| SCHEMBL3815494 | 0.87 | ALOX15 (0.35) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL3807725 | 0.87 | HSD17B1 (0.43) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL3811068 | 0.87 | KDM4E (0.39) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL2158728 | 0.86 | HSD17B1 (0.43) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL3807557 | 0.85 | HSD17B1 (0.40) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL3816598 | 0.85 | MAPT (0.35) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL3812533 | 0.85 | MAPT (0.38) | HSD17B1HSD17B2KDM4ENPC1POLB | |
| SCHEMBL3809515 | 0.84 | IKBKB (0.39) | KDM4ENPC1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |