Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816913 | 0.93 | LTB4R2 (0.42) | LTB4R2MAPTNPSR1HPGDALDH1A1 | |
| SCHEMBL3807560 | 0.92 | MAPT (0.40) | LTB4R2MAPTNPSR1HSD17B2HSD17B1 | |
| SCHEMBL3814659 | 0.91 | PTGES (0.46) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL3811293 | 0.90 | LTB4R2 (0.40) | LTB4R2MAPTNPSR1MEN1KMT2A | |
| SCHEMBL3815444 | 0.89 | MEN1 (0.40) | LTB4R2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL3812596 | 0.87 | PTGDR2 (0.45) | LTB4R2MAPTTRPM8HPGDALDH1A1 | |
| SCHEMBL3814627 | 0.86 | MAPT (0.38) | LTB4R2MAPTNPSR1HPGDALDH1A1 | |
| SCHEMBL3811333 | 0.85 | ALDH1A1 (0.40) | MAPTNPSR1TRPM8HPGDALDH1A1 | |
| SCHEMBL3807989 | 0.85 | TSPO (0.46) | LTB4R2MAPTHPGDALDH1A1RAB9A | |
| SCHEMBL3815372 | 0.84 | LTB4R2 (0.47) | LTB4R2MAPTNPSR1TRPM8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |